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Why is smoking bad for you? Is Nicotine Gum Harmful to Your Health? University Hospitals Cigarettes contain numerous harmful chemicals that damage nearly every organ in the body. Nicotine, one of the most well known substances, increases heart rate and blood pressure, contributing to cardiovascular issues. But nicotine Smoking: A Direct Hit to the Heart Every puff of a cigarette is a direct challenge to your cardiovascular system. Beyond the lungs, the chemicals in tobacco smoke enter your bloodstream Tobacco and Cancer Cancer CDC
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